Canonical Response Parameterization: Quantifying the structure of responses to single-pulse intracranial electrical brain stimulation
Fig 2
Quantifying single-trial cross-projections.
A. Stimulation and recording sites for this example, shown in an axial MRI section. B. 15 single trials of stimulation response (gray) produced the averaged evoked potential shape (black). C. Trial #1 (light blue) was unit-normalized and projected into the other 14 trials, omitting self-projection. D. As in (C), but for normalized trial #10 (orange). E. All 210 projections are shown sorted, note the obvious sub-sets corresponding to the projections of unit-normalized single trials. The projections of each trial into the others can reflect how representative each trial is of the canonical evoked potential response shape. F. The projections from (E), aggregated into a single column (i.e. imposing the assumption that the order of trials doesn’t matter, which will be false under some circumstances).