Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution
Fig 7
Overview of CompaCt output cluster containing subunits from the mitochondrial ATP Synthase complex in H. sapiens, P. knowlesi and T. gondii complexomes.
Clustered P. falciparum and H. sapiens proteins with a fraction clustered score of over 0.5 or best hit homologs of those are displayed, as well as their clustered Toxoplasma orthologs. Human proteins labeled “predicted mitochondrial” are listed in Mitocarta 3.0 [42]. Plasmodium and Toxoplasma proteins with this label are predicted as such by PlasmoMitoCarta [44] and a HyperLOPIT study [45], respectively.