Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution
Fig 3
Effect of including data from additional complexomes to CompaCt analysis on the agreement of H. sapiens cluster results with CORUM v4 [17].
Starting with only datasets representing the human complexome, datasets from additional complexomes were added to the analysis one by one, computing the MMR after including each. The remaining datasets are then added in a progressive manner, prioritizing those that resulted in the highest MMR increase. The y-axis displays the maximum matching ratio (MMR) between the human subclusters and the CORUM reference set of protein complexes, reflecting the overlap of the identified clusters with the reference. At each step the MMR resulting from including data from each remaining complexome is shown.