Data-driven segmentation of cortical calcium dynamics
Fig 8
Time series extracted from domain maps outperform time series generated from other down sampling methods.
(A) Example of a mosaic movie frame rebuilt with respect to each down sampling technique. The non-down sampled filtered movie is represented on the left with subsequent down sampling based on domain, grid or Voronoi maps. (B) Percent total signal of the filtered video represented by extracted time courses. Percent of overall video signal captured in domain maps was calculated for each animal (green circle; N = 8), and compared to signal content from a domain map generated from a separate video from the same animal (green triangle). Percent total signal represented by time courses extracted from grid (blue square) or randomly generated (blue diamond) maps were compared as controls. In the right panel, the percent signal relative to the domain map percent signal was summarized in a box plot. (C) Variation between time courses extracted with each map method was then quantified as a sum signal variation for each experiment. In the right panel, the sum signal variation for each comparison map relative to the optimized domain map sum signal variation was summarized in a box plot.