Pupillary response is associated with the reset and switching of functional brain networks during salience processing
Fig 5
Brain-pupil relationships of the cortical network-level effective connectivity (EC) and task-evoked pupillary response (TEPR) in salience processing.
(A) The oddball-modulated positive EC strength from the late-time to early-time network correlated with higher TEPR of oddball trials (p < 0.0035). In (B) and (C), to test the associations between pupil measurements and the triple-network model (SN, salience network; DAN, dorsal attention network; DMN, default mode network), we computed EC across nodes of these networks. (B) The oddball-modulated positive EC strength from SN to DAN correlated with higher TEPR of oddball trials (p < 0.0013). (C) The oddball-modulated negative EC strength from SN to DMN correlated with higher TEPR of oddball trials (p < 0.0060).