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Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals

Fig 5

Partial Correlation Network topologies.

(a) shows the network density (fraction of all possible gene pairs that have an edge) and (b) shows the size of the largest connected component (the highest number of nodes that are connected to each other directly or through other nodes). Each network is identified by the set of parameters used to compute the Partial Correlation (n_genes, min_lambda). n_genes is the number of controlling genes and min_lambda is the normalization parameter, which are used to compute the partial correlation.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1011079.g005