Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks
Fig 4
rTMS intensity and pulse number affect the structural remodeling of the stimulated population (S).
(A) Interrelation between the S − S connectivity drop during stimulation (ΔCstim) and S − S connectivity increase post stimulation (ΔCpost). (B) S − S connectivity changes from different pulse numbers of 10 Hz stimulation at peak stimulation intensity (c, as defined in Fig 2C). (C) Saturation points of S − S connectivity, expressed in the form of total pulse numbers required to reach saturation, are summarized for a range of frequencies. (D) Time constants of connectivity decay (τdecay) were extracted by fitting an exponential function to connectivity drop among stimulated neurons (S–S).