MultiCens: Multilayer network centrality measures to uncover molecular mediators of tissue-tissue communication
Fig 2
Synthetic multilayer network construction.
(A) Synthetic network construction starts with a base random multilayer network with edge probability 0.05; (B) On the base synthetic multilayer network, more edges are added, according to the connection strength desired, both within the selected communities (indicated by circles) and between certain pairs of communities (indicated by thick dark edges connecting the pair; e.g. between source set 1 and source set 2). In the second layer, when only one community, query-set, is used, we call this model as the Synthetic Multilayer Network Model 1. When another community (marked in dotted circle) is connected to the query-set, we call this configuration Synthetic Multilayer Network Model 2.