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Distilling identifiable and interpretable dynamic models from biological data

Fig 3

Immunity model.

Structural unidentifiability in CM (unidentifiable parameters in red, identifiable parameters in blue) leads to the same output dynamics when different parameterizations are considered, as can be seen in CM2. In contrast, the reformulation M* is FISPO and therefore there is a unique set of parameters compatible with the output measurements.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1011014.g003