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Modeling the progression of Type 2 diabetes with underlying obesity

Fig 3

Comparison of the insulin sensitivity and GIβ dynamics using C(I) and C(I, X) in the model.

The function C(I, X) is chosen to be , where C(I) is given in model (1). The other parameters maintain the same as in Fig 2. Graph (a) shows the time evolution of the insulin sensitivity C(I) in the dashed curve and C(I, X) in the solid curve. Graphs (b), (c), and (d) exhibit the corresponding GIβ dynamics under the two insulin sensitivity functions.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1010914.g003