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Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

Fig 14

Summary of the results in Fig 13.

Left panel: The upstroke duration for the membrane potential of the pre-junctional cell as a function of the membrane area Ly × Lz.This upstroke duration corresponds to the time for the membrane potential of the pre-junctional cell to increase from the resting potential to v = 30 mV after the INa channel cluster has been opened. Right panels: The minimum value of ϕ and [Na+] and the maximum value of [K+] outside of the Na+ channel cluster of the pre-junctional cell (solid lines) and at the level of the post-junctional membrane facing the cluster (dashed lines), as well as the minimum value of INa (the INa peak) of the pre-junctional cell as functions of the membrane area.

Fig 14

doi: https://doi.org/10.1371/journal.pcbi.1010895.g014