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Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

Fig 12

Largest deviations from rest in the extracellular potential and ion concentrations outside of the Na+ channel clusters in simulations with different widths of the extracellular space between the cells, Le, and different sizes of the Na+ channel clusters.

The full lines show the solution outside of the Na+ channel cluster of the pre-junctional cell, which has open Na+ channels. The dotted lines show the solution on the other side of the extracellular space, outside of the post-junctional cell, which has closed Na+ channels.

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1010895.g012