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Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

Fig 4

Illustration of an example mesh for Le = 15 nm and Li = 50 nm in the (x, y)- and the (x, z)-planes.

The intracellular domain is colored orange, the extracellular domain is colored pink, the membrane is colored green and the ion channels are colored purple. In this figure, we consider K+ and Na+ channel clusters consisting of 2×2 channels of each type in the membrane of both cells. In the (x, y)-plane, the two types of ion channel are located as different locations (different y-values), whereas in the (x, z)-plane the two types of ion channel overlap because they are located at the same z-values. The mesh in the area close to the ion channels (indicated by dashed lines) is shown in more detail on the right side of the figure.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1010895.g004