Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses
Fig 2
Prediction of tissue damage for H1N1 viruses.
The violin plots (coloured) and boxplots (white) give the density and the median and extrema of the predicted quantity. (A) model prediction of the maximal epithelium loss for the HP (yellow) and LP (green) strains. (B) model prediction of the cumulative level of dead cells during the infection for both strains. ***p<0.001. For calculation formulas see Eqs 11 and 12 in the Materials and methods. All estimations are computed using 6000 posterior samples from model fitting. The estimations for the H5N1 viruses are given in S3 Fig.