AimSeg: A machine-learning-aided tool for axon, inner tongue and myelin segmentation
Fig 5
Agreement between the validation ground truth and the AimSeg measurements for the analysis of myelin properties.
(A) Example image for the semantic segmentation of the fibres. Scale bar (white line) = 1 μm. (B) Comparison of the fibre areas obtained by manually segmenting the images or using AimSeg. (B, left) The measurement agreement is calculated as the Lin’s concordance correlation coefficient (CCC), (B, right) while the measurement bias is assessed by means of a Bland-Altman analysis. Diagonal line in the CCC plot represents perfect agreement (y = x). (C) Illustration of the myelin g-ratio measurement, calculated as the ratio of the inner region diameter to the fibre diameter. (D) Illustration of the axon g-ratio measurement, calculated as the ratio of the axon diameter to the fibre diameter. CCC and Bland-Altman plot for (E) the myelin and (F) the axon g-ratios.