Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens
Fig 5
Comparison of 200 simulations for all HRZEM four–way regimens using GranSim.
Comparison of (A–C) sterilizing rates and (D–F) sterilization times of 4–way combinations of HRZEM for (A and D) 100 high–CFU, (B and E) 100 low–CFU and (C and F) a combination of 100 high–and 100 low–CFU granulomas. Significance test was performed only between HRZE and moxifloxacin–containing regimens (*p<0.0001, one–tailed paired t–test). The central lines in box plots represent the median, whereas the bottom and the top edges of boxes represent 25th and 75th percentiles, respectively.