A quantitative model for human neurovascular coupling with translated mechanisms from animals
Fig 3
Model estimation to experimental data in Section 2.1.1.
Data and simulations for arteriolar (A–C) and venular (D–F) diameter changes in awake mice for three different sensory stimulation lengths: 125 ms (A & D), 10 s (B & E), and 30 s (C & F). Experimental data are replotted versions of data presented in Fig 2C of the original manuscript by Drew et al. [46]. The stimulation lengths are denoted with the black bar in the bottom left portion of each graph. For each graph: experimental data (colored symbols); the uncertainty of the experimental data is presented as the standard error of the mean (SEM) (colored error bars); the best model simulation is seen as a colored solid line; the model uncertainty as a colored semi-transparent overlay. The x-axis represents time in seconds, and the y-axis is the normalized vessel diameter change (Δ%).