Interacting active surfaces: A model for three-dimensional cell aggregates
Fig 7
Growth of small cell aggregates, driven by synchronous cell divisions and cell volume increase (,
,
).
(A) Each cell doubles its volume between birth and division, over a cell cycle time tD. Cell division is introduced by splitting the mother cell with a plane passing through the cell centre, and generating two daughter cells separated by a distance d* (d*/2 from the division plane). (B-D) Simulation results for two values of the ratio τ/tD. (B): Largest centre-to-centre cell distance max〈I,J〉 RIJ, as a function of time. Jumps correspond to cell division events. (C) Average reduced volume 〈v〉 as a function of time. (D) Snapshots of simulations of two growing aggregates.