HiSV: A control-free method for structural variation detection from Hi-C data
Fig 5
Effects of SVs on gene expression in K562 cell line.
(A) Volcano plot showing differentially expressed genes (DEGs); red dots represent upregulated genes; blue dots represent downregulated genes and gray dots represent genes with no expression changes. (B) Comparison of the genes in SV regions with DEGs. (C) The overlap counts of DEGs in novel SV regions and common SV regions. (D) The differential expression of GPC5 is associated with neo-loops. (E) The upregulated expression of DLGAP1 is associated with an enhancer hijacking event.