HiSV: A control-free method for structural variation detection from Hi-C data
Fig 4
Complex SVs were detected by HiSV.
Intra-chromosomal complex SVs were detected in K562 (A) and T47D (B) by HiSV. The top shows the Hi-C maps with complex SVs and boxes represent the SVs event detected by HiSV. The plot in the middle depicts breakpoint connections that are detected from long-read sequencing data. The bottom panel shows the genome structure of the complex SVs. Inter-chromosomal complex SVs were detected in T47D (C) and K562 (D) by HiSV. The top panel shows Hi-C maps with complex SVs. The circos plot in the below, from outside to inside, depicts the chromosome ideogram, copy number profiles and breakpoint connections. The black arcs are the SVs detected from long reads data and red arcs represent the inter-chromosomal rearrangements detected by all Hi-C methods.