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Identifying a developmental transition in honey bees using gene expression data

Fig 5

Fitting to the Landau probability density function performs better than a mixture of two Gaussians.

In tests with simulated data, the Landau method (A) identifies the transition state sooner (at smaller μ, when the bistable states are closer to one another; shown here fitting 100 samples), and (B) fits the transition distribution much more closely (shown here fitting 50,000 samples at μ = 0.0158; simulated data in blue histogram compared to best fits of Landau distribution and Gaussian mixture distribution shown as solid curves). Error bars in (A) indicate estimated standard deviation of the mean given 100 simulations.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1010704.g005