Computational analysis of 5-fluorouracil anti-tumor activity in colon cancer using a mechanistic pharmacokinetic/pharmacodynamic model
Fig 4
Time-dependent outputs of the 9 TGI model using parameter estimates shown in Table 4.
Red line represents the time course of the control group; blue line represents the time course of colon tumor growth treated with corresponding dosage regimens shown in Table 3; triangle, literature data for the control group; circle, literature data for the treated group; error bar, standard errors; asterisk on x-axis represents injection time. The shaded areas in each panel represent the 0.7 credible intervals.