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Sampling effects and measurement overlap can bias the inference of neuronal avalanches

Fig 6

In vivo and in vitro avalanche-size distributions p(S) from LFP depend on time-bin size Δt.

Experimental LFP results are reproduced by many dynamics states of coarse-sampled simulations. A: Experimental in vivo results (LFP, human) from an array of 60 electrodes, adapted from [43]. B: Experimental in vitro results (LFP, culture) from an array with 60 electrodes, adapted from [1]. C–F: Simulation results from an array of 64 virtual electrodes and varying dynamic states, with time-bin sizes between 2 ms ≤ Δt ≤ 16 ms, γ = 1 and dE = 400 μm. Subcritical, reverberating and critical dynamics produce approximate power-law distributions with bin-size-dependent exponents α. Insets: Log-Log plot, distributions are fitted to p(S) ∼ Sα, fit range S ≤ 50. The magnitude of α decreases as Δtβ with −β indicated next to the insets, cf. Table 2.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1010678.g006