HELIOS: High-speed sequence alignment in optics
Table 5
The parameter Similarity of the Smith-Waterman algorithm in the quantitative measurement of homology.
The Similarity measures the resemblance of two compared sequences (in percentage) aligned by the HELIOS method. Various amino acids are categorized into six groups based on their physicochemical properties; including GAVLI, FYW, STCM, KRH, DENQ, and P. Moreover, the “Nine ND5 protein sequences dataset” [53] is assumed in this study.