HELIOS: High-speed sequence alignment in optics
Fig 7
Modulation approach of the HELIOS Optical architecture, utilizing the wavelength and polarization of the optical beams.
To implement the self-label coding through the wavelength modulation approach, every character of the input sequence is modulated with a distinct wavelength, within the spectral range of [450–650] nanometers with bandwidth of 10 nanometers. On the other hand, to implement the nearby-label coding through the polarization selection approach, every character of the input sequence is assigned to a specific polarization along a 9-degree azimuth angle in the range of 0 to 180 degrees. Each approach provides twenty distinct codes for protein sequences, while only four of them are employed for coding DNA and RNA sequences.