Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band
Fig 3
Identification of most relevant oscillators and investigation of their spectral properties.
(A) Rationale about the selection of salient nodes in the BG network for a single simulation run. The nodes, taken together, define the STR and the STN loops (in blue and red shadow respectively). (B) STR loop with FSN, GPe-TI and D2 nuclei, connected with feedforward inhibitory projections (in red) and with their natural mode. (C) STN loop with STN and GPe-TI nuclei, connected with excitatory feedforward (in green) and inhibitory feedback projections (in red) and their natural mode.