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A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls

Fig 5

Renal K+ response to a single meal.

Model simulation predictions for kidney K+ handling during a single meal load. The meal experiment occurs at time = 0 hours. Initial conditions are the baseline steady state values (see Table 2) with a fasting state before the meal experiment. The yellow lines denote the K+ deficient meal (i.e., “Meal only” experiment); purple, only K+ ingestion (i.e., “KCl only” experiment); blue, meal with K+ (i.e., “Meal + KCl” experiment). Points and error bars for urine K+ excretion show experimental data from Preston et al. [17].

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1010607.g005