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A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls

Fig 2

Model schematic.

Flow chart depicting our mathematical model of K+ regulation. Green nodes represent internal K+ balance; orange, kidney function; blue, hormones (i.e., ALD and insulin); and white, constant model parameters. Pointed arrows indicate stimulation; blunted arrows indicate inhibition. ALD: aldosterone, GFR: glomerular filtration rate, GI: gastrointestinal, Interstitial: interstitial fluid, ICF: intracellular fluid, ECF: extracellular fluid

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1010607.g002