Identifying the genes impacted by cell proliferation in proteomics and transcriptomics studies
Fig 5
Proliferation signature in the context of cancer grade.
a-b) Enrichment of the proliferation signature in proteins associated with cancer stage (a) and grade (b). Proteins were ranked by significance of correlation according to Monsivais et al. [6] (p-value of Pearson correlation) (horizontal axis) and the vertical axis presents the cumulative number of signature genes for each cancer type. d) Proteins T-statistic provided by Monsivais et al. [6] for the analysis of cancer grades (positive = high correlation with cancer grade) for each cancer type (horizontal axis). Each point corresponds to a protein, signature genes are highlighted in orange. The seven top hits for each cancer type are indicated by their gene names.