Variant calling enhances the identification of cancer cells in single-cell RNA sequencing data
Table 2
Gene set enrichment analysis results showing top 10 enriched cancer hallmark gene sets by enrichment score for groups of driver enriched cells versus all others.
Top section shows enrichment when comparing cells with high putative driver counts to cells with low putative driver counts for the CRC dataset. Middle section shows enrichment when comparing ERBB2+/PIK3CA+ cells to cells lacking the characteristic ERBB2 or PIK3CA mutations for the CRC dataset. Bottom section shows enrichment when comparing cells with high putative driver counts to cells with low putative driver counts for the TNBC dataset.