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Synaptic reshaping of plastic neuronal networks by periodic multichannel stimulation with single-pulse and burst stimuli

Fig 12

PMCS-induced feed-forward and circular network structure.

A: Raster plot of simulated spiking activity in the LIF network model 1000 sec after onset of PMCS with single-pulse stimuli and small positive phase lags between subsequent subpopulations. B: Snapshots of simulated synaptic weight matrix after 1000 sec of stimulation (sim) and the corresponding theoretical prediction obtained from Eq 1 (theory). C: Schematic of stimulation-induced feed-forward structure (see caption of Fig 9 for symbols). A’-C’: Same as A-C but for slow PMCS with long single-pulse stimuli. The phase lags were adjusted to cause a circular network structure. Parameters: Astim = 0.4 and Δα1/2 = 0.3 (A-C), and Δα1/2 = 0.33 (A’-C’) and de = 1 and f = 10 Hz (A-C), and de = 20 and f = 2.5 Hz (A’-C’).

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1010568.g012