Synaptic reshaping of plastic neuronal networks by periodic multichannel stimulation with single-pulse and burst stimuli
Fig 10
PMCS can be employed to modulate intra- and inter-population synapses in opposite ways.
A: Raster plot of simulated spiking activity for PMCS with burst stimuli with high intraburst frequency. B: Snapshots of simulated synaptic weight matrix after 1000 sec of stimulation (sim) and the corresponding theoretical prediction obtained from Eq 1 (theory). C: Schematic of stimulation-induced network structure (see caption of Fig 9 for symbols). A’-C’: Same as A-C but for burst stimuli with low intraburst frequency. Parameters: Astim = 0.8, f = 5 Hz, and de = 1 (all panels). In panels A-C, we used an intraburst frequency of 120 Hz, three pulses per burst, and Δα1/2 = 0.33 (A-C), In panels A’-C’, we used 60 Hz, eight pulses per burst, and Δα1/2 = 0.31 (A’-C’).