Synaptic reshaping of plastic neuronal networks by periodic multichannel stimulation with single-pulse and burst stimuli
Fig 3
Effect of PMCS with (M = 2) on the mean weight of synapses with postsynaptic neuron in subpopulation 2 and presynaptic neuron in subpopulation 1 as function of the phase lag, Δα, between stimulus trains delivered to the two subpopulations.
Panels show results for single-pulse (A-C) and burst stimuli with three (A’-C’) and five (A”-C”) pulses per burst. Results for high (120 Hz) and low (60 Hz) intraburst frequencies are shown in red and blue, respectively. Curves show theoretical approximations (Eq 19) and markers
obtained from simulations and averaged over five network realizations and initial conditions (Methods). Parameters: de = 1 and Astim = 0.4 (A,B,C), Astim = 0.8 (A’-C’, A”-C”). Note that different intervals are plotted on the y-axes.