Chaos in synthetic microbial communities
Fig 4
A Topology of m850 with key parameters labelled. kA1 is the rate of QS molecule production, KBmax1 and KBmax2 are the maximal expression rates of bacteriocins B1 and B2 respectively. B Posterior parameter distributions of m850 for chaos (red) and oscillatory (blue) objectives for key parameters in system design. The borders show 1D posterior distributions for each parameter and the lower-diagonal element the 2D posterior marginals, and the upper-diagonal shows the Pearson correlations. C Feature importance calculated using random forest regression. The information gain (bits) is calculated as an average of the reduction in entropy across all trees in the forest (2000 trees). The error bars indicate the standard deviation of the entropy for each feature across all trees. D Sensitivity analysis of a chaotic input vector with chaotic region in red. Black stars refer to the identified stable steady state. The fixed parameter values are shown in Table 2