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Calibrating spatiotemporal models of microbial communities to microscopy data: A review

Fig 2

Single-cell measurement techniques for microbial communities.

(a) Flow cytometers can measure cell fluorescence and morphology in large sample sizes. (b) Time-lapse microscopy allows for direct visualization of physical cell–cell interactions and quantitative measurement of single-cell characteristics over time. (c) End-point microscopy can illustrate large-scale spatial patterns and features of cell arrangements in 2 or 3 dimensions.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1010533.g002