On the incongruence of genotype-phenotype and fitness landscapes
Fig 2
Local incongruence: Magnitude epistasis.
(A) The probability of retaining the type of epistasis, shown in relation to the optimal phenotype wopt. The black line shows the theoretical prediction and the dots show the results from randomly generated genotype-phenotype landscapes for different values of σ. The theoretical approximation agrees well with the results from randomly generated genotype-phenotype landscapes for large σ (i.e., σ ≥ 1). (B) The probability of observing zero magnitude epistasis in the fitness landscape, shown in relation to wopt, for different values of σ, which we selected to show the range of variation in the probability of observing zero epistasis.