Cross-GWAS coherence test at the gene and pathway level
Fig 9
Manhattan plot for ratio scoring Vitamin D concentration against severe COVID-19 in the coherent case, with ratio denominator given by COVID-19.
The Bonferroni significance threshold of p = 3.4 × 10−7 is indicated by the red dotted line (0.05 divided by the 18453 genes and 2 times 4 traits tested).