Cross-GWAS coherence test at the gene and pathway level
Fig 6
Left: SNP p-values after rank transform for the CCR3 gene.
The x-axis is numbered according to the ith SNP in the gene window ordered by increasing position. The dotted black lines indicate the transcription start and end positions (first and last SNP). Up bars correspond to M05B and down bars to severe COVID-19. Green indicates positive and violet negative association with the trait. Right: SNP-SNP correlation matrix inferred from the 1KG reference panel. The color scale is shown on the right with dark red (+1) corresponding to perfect SNP-SNP correlation and dark blue (−1) to perfect anti-correlation over the reference population.