Cross-GWAS coherence test at the gene and pathway level
Fig 5
Manhattan plot for cross scoring very severe confirmed COVID-19 with medication class M05B for coherence.
Data points correspond to genes. The dotted red line marks a Bonferroni significance threshold of 1.18 × 10−7 (0.05 divided by the 18453 genes tested and 23 drug classes). The inlay plot shows a zoom into the relevant locus chr3p21.31.