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The osteogenetic activities of mesenchymal stem cells in response to Mg2+ ions and inflammatory cytokines: a numerical approach using fuzzy logic controllers

Fig 6

Fits of the model calibrated by C1-5 and C4 to the empirical data of study 4.

Bars indicate the simulations (S) and the corresponding empirical data (E). The quantities of ALP and ARS are reported at day 3 and 9, respectively. The data is presented in a relative fold compared to the control, i.e. the undifferentiated case encoded as ctr. The error bars on the empirical data shows the standard deviations. The error bars on the simulation results show the standard deviations obtained during SSIP, i.e. 15% alteration in the estimated parameter values. Stars indicate the statistically significant differences between values given for the empirical data compared to the control (p < 0.05 = *). is the average fitness value of the simulations for the given measurement item.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1010482.g006