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The osteogenetic activities of mesenchymal stem cells in response to Mg2+ ions and inflammatory cytokines: a numerical approach using fuzzy logic controllers

Fig 2

Fits of the model calibrated by C1-5 and C1 to the empirical data of study 1.

Bars indicate the simulations (S-) and the corresponding empirical data (E-) for increasing Mg2+ ion concentrations. The error bars on the empirical data show the standard deviations. The error bars on the simulation results show the standard deviations obtained during SSIP, i.e. 15% alteration in the estimated parameter values. Stars indicate the statistically significant differences between values given for the empirical data compared to the control, i.e. Mg2+ ion concentration of 0.08 mM (p < 0.05 = *; p < 0.01 = **). is the average fitness value of the simulations for the given measurement item.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1010482.g002