Digital twin predicting diet response before and after long-term fasting
Fig 7
Simulations of five common diet schemes and varying different personalized variables.
(A) The model considers diets with different meal frequencies, ranging from Intermediate Fasting (IF) with two meals (depicted as black bars), to 5:2 with 2–3 meals, and even SFM (with three smaller meals). These three diets are isocaloric. (B) The model can also to some extent simulate different compositions, such as LCHF (low carbohydrate, high fat diet), and HCLF (high carbohydrate, low fat diet). (C) Mean values of key variables during the second week after the diet has started. (D) Impact of changing the rate of consumption. E) Impact of changing the body weight by 30 kg, while keeping all other variables constant. All simulations in A-D were done using a male who was 180 cm, 80 kg, and in E that male either weighed 110 or 80 kg.