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Constructing functional models from biophysically-detailed neurons

Fig 12

Architecture for the biologically-constrainted DRT neural network.

This network extends Fig 10 by (a) replacing “inh” with a population of detailed inhibitory interneurons, (b) adding a “cleanup” network that uses WTA competition to find the cue location that best resembles the recalled location from “pop” (see [26] for a detailed description), and (c) replacing all connections to/from detailed neurons with conductance-based AMPA, GABA, or (voltage-gated) NMDA synapses. Grey populations contain LIF neurons, orange populations are interneurons, and blue populations are pyramidal cells. Pink connections use AMPA synapses, orange connections GABA synapses, and green connections use NMDA synapses.

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1010461.g012