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Is cell segregation like oil and water: Asymptotic versus transitory regime

Fig 7

The cellular automaton with γ-ρ-fitted parameters reproduces the morphology and size distribution of the cell clusters ρ in the experiments of Méhes et al. [20] of EPC (green) with PFK (red) closer than the cellular automaton with the γ-fitted parameters.

The snapshots of the cell mixtures A, C, E of the first row are taken at a segregation index of EPC γEPC = 0.25, at the start of the experimental recording, while the snapshots B, D, F in the second row are at a segregation index of EPC γEPC = 0.1, at the end of the recording. A and B show the cellular automaton with optimised parameters, C and D show the experiments and are taken from video S5 in Méhes et al. [20], and E and F show the cellular automaton with the Δγ fitted parameters. The snapshots A, B, E and F show a detail from the simulations, such that approximately 1002 cells are visible, to match the spatial scale of the snapshots C and D of the experiments.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1010460.g007