Robust inference of population size histories from genomic sequencing data

doi:10.1371/journal.pcbi.1010419

Robust inference of population size histories from genomic sequencing data

Fig 10

Results of inference using 10 pseudo-haploids simulated under the piecewise sawtooth demography.

We compare the results of CHIMP- using the pseudo-haploid option, MSMC2, and Relate, fixing the change points to match the truth (shown in black). Solid lines are averages over 16 replicates and shaded area indicates standard deviation. Mean signed error Δ(k) is shown in bottom plot and has been smoothed using moving average for visualization purposes. The integral ϕ is indicated in the legend. Note that Relate entirely failed to estimate a population size in the most recent epochs, resulting in indeterminate values.

doi: https://doi.org/10.1371/journal.pcbi.1010419.g010