Robust inference of population size histories from genomic sequencing data
Fig 5
Results of inference in the piecewise sawtooth scenario from a sample of size n = 10 for different subset sizes using either TMRCA (Panel A) or (Panel B) as the hidden state.
We infer the population sizes in the intervals, fixing the change points to match the truth (shown in black). For CHIMP, we use non-overlapping subsets of sizes ns = 2, 5, and 10. For ns = 2, we also present overlapping subsets (-o). We present results obtained using MSMC2 for comparison. Solid lines are averages over 16 replicates and the standard deviation is indicated by the shaded areas. Mean signed error Δ(k) is shown in bottom plot and has been smoothed using moving average for visualization purposes. The integral ϕ is indicated in the legend. Note that MSMC2 groups epochs in the very distant past due to limits of the method interface.