Mathematical modeling to understand the role of bivalent thrombin-fibrin binding during polymerization
Fig 6
Protofibril number and structural quantities after long periods of time: Comparing model output with experiments.
Shown are the experimentally measured fiber radii [32] in (A). Model outputs as a function of both the thrombin concentration and γ′:E-domain ratio: (B) protofibril number, (C) protein density and (D) distance between protofibrils. The quantities in C,D are computed by combining the measurements in A with a post-processing of the model output in B.