A multi-objective based clustering for inferring BCR clonal lineages from high-throughput B cell repertoire data
Fig 13
Clonal distribution of healthy donors and patients with moderate/severe COVID-19.
A) Abundance of top 20 ranked clonal groups stratified by clinical status. We plotted each individual’s most abundant clonal groups until achieving 20 samples. B) Abundance of top 20 ranked clonal groups stratified by individuals. C) CDR3 nucleotide lengths of the top 20 clonal groups, stratified by clinical status. In panels A and B, circles represent clonal lineages, while their areas are proportional to the clonal group abundance. Each color represents an individual. Report to Table 4 for repertoire properties and individuals’ labels. Abbreviations: S-severe and M-moderate COVID-19; H-healthy donors.