A multi-objective based clustering for inferring BCR clonal lineages from high-throughput B cell repertoire data
Fig 6
Impact of refinement parameters in the best and worst performance.
We averaged F-scores of 12 simulated repertoires and ranked them to form two sets of parameter configurations: those with the best performance (F-score = 1) and those with the worst performance (lowest F-score < 0.7). The ordinate shows parameter frequency and abscissa parameter type. (A, B, and C) show IGHV, IGHJ, and CDR3 distances, while (D) shows coefficient variations. Note that d––– indicates the coefficient values for α, β, and λ respectively, while ‘mean’ represents the arithmetic mean.