Multiscale modelling of desquamation in the interfollicular epidermis
Fig 3
Diagram of the coupling between the multicellular and the subcellular scales.
Cells are coloured by their proportion of remaining corneodesmosome. The cell gets its vertical location, normalised by corneum thickness and start height, (ΞΎi) from the multiscale model, updates the subcellular model parameters and solves for that time step, and then returns the updated proportion of remaining corneodesmosomes (si) to the multicellular model to scale cell-cell adhesion ().